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1

Second Primary Tumors in Head and Neck Cancer Patients

Le&#x000F3, n, Xavier, Ferlito, Alfio, III, Charles M. Myer, Saffiotti, Umberto, Shaha, Ashok R., Bradley, Patrick J., Brandwein, Margaret S., Anniko, Matti, Elluru, Ravindhra G., Rinaldo, Alessandra

Journal:

Acta Oto-Laryngologica

Year:

2002

Language:

english

File:

PDF, 233 KB

english, 2002

2

Transforming growth factor beta expression and transformation of rat lung epithelial cells by crystalline silica (quartz)

A. Olufemi Williams, Alan D. Knapton, Ekwere T. Ifon, Umberto Saffiotti

Journal:

International Journal of Cancer

Year:

1996

Language:

english

File:

PDF, 1.53 MB

english, 1996

3

Ultrastructural effects of N-methyl-N-nitrosourea on the tracheobronchial epithelium of the Syrian Golden hamster

Curtis C. Harris, David G. Kaufman, Michael B. Sporn, Joseph M. Smith, Frank Jackson, Umberto Saffiotti

Journal:

International Journal of Cancer

Year:

1973

Language:

english

File:

PDF, 1.42 MB

english, 1973

4

Releasing carcinogenesis test results: Timing and extent of reporting

Umberto Saffiotti, Norbert P. Page

Journal:

Pediatric Blood & Cancer

Year:

1977

Language:

english

File:

PDF, 578 KB

english, 1977

5

Generation of thiyl and ascorbyl radicals in the reaction of peroxynitrite with thiols and ascorbate at physiological pH

Xianglin Shi, Yan Mao, Lambert N. Daniel, Nadera Ahmed, Umberto Saffiotti, Yongyut Rojanasakul, Peter Gannett, Kejian Liu

Journal:

Journal of Inorganic Biochemistry

Year:

1994

Language:

english

File:

PDF, 674 KB

english, 1994

6

Vanadium(IV)-mediated free radical generation and related 2′-deoxyguanosine hydroxylation and DNA damage

Xianglin Shi, Hengguang Jiang, Yan Mao, Jianping Ye, Umberto Saffiotti

Journal:

Year:

1996

Language:

english

File:

PDF, 1010 KB

english, 1996

7

Atypical cilia in the tracheobronchial epithelium of the hamster during respiratory carcinogenesis

Curtis C. Harris, David G. Kaufman, Frank Jackson, Joseph M. Smith, Paul Dedick, Umberto Saffiotti

Journal:

The Journal of Pathology

Year:

1974

Language:

english

File:

PDF, 507 KB

english, 1974

8

CUTANEOUS CHEMICAL CARCINOGENESIS: PAST, PRESENT, AND FUTURE.

Yuspa, Stuart H., Hennings, Henry, Saffiotti, Umberto

Journal:

The Journal of Investigative Dermatology

Year:

1976

File:

PDF, 7.74 MB

1976

9

α and β-Retinyl acetate reverse metaplasias of vitamin A deficiency in hamster trachea in organ culture

CLAMON, GERALD H., SPORN, MICHAEL B., SMITH, JOSEPH M., SAFFIOTTI, UMBERTO

Journal:

Year:

1974

File:

PDF, 328 KB

1974

10

Altered expression of adhesion molecules and epithelial–mesenchymal transition in silica-induced rat lung carcinogenesis

Blanco, David, Vicent, Silvestre, Elizegi, Eider, Pino, Irene, Fraga, Mario F, Esteller, Manel, Saffiotti, Umberto, Lecanda, Fernando, Montuenga, Luis M

Journal:

Laboratory Investigation

Year:

2004

Language:

english

File:

PDF, 717 KB

english, 2004

11

Hyperplasia of Alveolar Neuroendocrine Cells in Rat Lung Carcinogenesis by Silica with Selective Expression of Proadrenomedullin-Derived Peptides and Amidating Enzymes

Elizegi, Eider, Pino, Irene, Vicent, Silvestre, Blanco, David, Saffiotti, Umberto, Montuenga, Luis M

Journal:

Laboratory Investigation

Year:

2001

Language:

english

File:

PDF, 2.91 MB

english, 2001

12

Dose-response studies on neoplastic transformation of BALB/3T3 clone A31-1-1 cells by aflatoxin B1, benzidine, benzo[a]pyrene, 3-methylcholanthrene, and N-methyl-N′-nitro-N-nitrosoguanidine

Enrico Cortesi, Umberto Saffiotti, Paul J. Donovan, Jerry M. Rice, Takeo Kakunaga

Journal:

Teratogenesis, Carcinogenesis, and Mutagenesis

Year:

1983

Language:

english

File:

PDF, 594 KB

english, 1983

13

Neoplastic transformation by quartz in the BALB/3T3/A31-1-1 cell line and the effects of associated minerals

Dr. Umberto Saffiotti, Nadera Ahmed

Journal:

Teratogenesis, Carcinogenesis, and Mutagenesis

Year:

1995

Language:

english

File:

PDF, 1.11 MB

english, 1995

14

Neoplastic transformation of BALB/3T3 cells by metals and the quest for induction of a metastatic phenotype

Umberto Saffiotti, Federico Bertolero

Journal:

Biological Trace Element Research

Year:

1989

Language:

english

File:

PDF, 496 KB

english, 1989

15

Oxidative DNA damage by crystalline silica

Lambert N. Daniel, Yan Mao, Saffiotti Umberto

Journal:

Free Radical Biology and Medicine

Year:

1993

Language:

english

File:

PDF, 2.83 MB

english, 1993

16

DISCUSSION OF PART VIII: METHODOLOGIES FOR RISK ASSESSMENT

Umberto Saffiotti

Journal:

Annals of the New York Academy of Sciences

Year:

1976

Language:

english

File:

PDF, 277 KB

english, 1976

17

PREVENTION OF OCCUPATIONAL CANCER—TOWARD AN INTEGRATED PROGRAM OF GOVERNMENTAL ACTION: ROLE OF THE NATIONAL CANCER INSTITUTE

Umberto Saffiotti

Journal:

Annals of the New York Academy of Sciences

Year:

1976

Language:

english

File:

PDF, 343 KB

english, 1976

18

METHODOLOGIES FOR RISK ASSESSMENT IN OCCUPATIONAL CARCINOGENESIS

Umberto Saffiotti

Journal:

Annals of the New York Academy of Sciences

Year:

1976

Language:

english

File:

PDF, 173 KB

english, 1976

19

Carcinogenesis of laryngeal carcinoma

Umberto Saffiotti, David G. Kaufman

Journal:

The Laryngoscope

Year:

1975

File:

PDF, 1.13 MB

1975

20

Mouse epidermal keratinocytes: Clonal proliferation and response to hormones and growth factors in serum-free medium

Federico Bertolero, M.Edward Kaighn, Matthew A. Gonda, Umberto Saffiotti

Journal:

Experimental Cell Research

Year:

1984

Language:

english

File:

PDF, 8.65 MB

english, 1984

21

Activity of vitamin A analogues in cell cultures of mouse epidermis and organ cultures of hamster trachea

SPORN, MICHAEL B., CLAMON, GERALD H., DUNLOP, NANCY M., NEWTON, DIANNE L., SMITH, JOSEPH M., SAFFIOTTI, UMBERTO

Journal:

Year:

1975

File:

PDF, 380 KB

1975

22

Skin tumorigenesis by an extract of amber petrolatum

William Lijinsky, Umberto Saffiotti, Philippe Shubik

Journal:

Toxicology and Applied Pharmacology

Year:

1966

Language:

english

File:

PDF, 303 KB

english, 1966

23

Comments on the scientific basis for the “Delaney Clause”

Umberto Saffiotti

Journal:

Preventive Medicine

Year:

1973

Language:

english

File:

PDF, 645 KB

english, 1973

24

Experimental Identification of Chemical Carcinogens, Risk Evaluation, and Animal-to-Human Correlations

Umberto Saffiotti

Journal:

Environmental Health Perspectives

Year:

1978

Language:

english

File:

PDF, 366 KB

english, 1978

25

Supplement 10: Oxygen Radicals and Lung Injury || DNA Binding to Crystalline Silica Characterized by Fourier-Transform Infrared Spectroscopy

Yan Mao, Lambert N. Daniel, Noel Whittaker and Umberto Saffiotti

Journal:

Environmental Health Perspectives

Year:

1994

Language:

english

File:

PDF, 1.43 MB

english, 1994

26

Supplement 10: Oxygen Radicals and Lung Injury || Mechanisms of Carcinogenesis by Crystalline Silica in Relation to Oxygen Radicals

Umberto Saffiotti, Lambert N. Daniel, Yan Mao, Xianglin Shi, A. Olufemi Williams and M. Edward Kaighn

Journal:

Environmental Health Perspectives

Year:

1994

Language:

english

File:

PDF, 1.25 MB

english, 1994

27

Supplement 10: Oxygen Radicals and Lung Injury || Silica Radical-Induced DNA Damage and Lipid Peroxidation

Xianglin Shi, Yan Mao, Lambert N. Daniel, Umberto Saffiotti, Nar S. Dalal and Val Vallyathan

Journal:

Environmental Health Perspectives

Year:

1994

Language:

english

File:

PDF, 1.32 MB

english, 1994

28

Relationship between Surface Properties and Cellular Responses to Crystalline Silica: Studies with Heat-Treated Cristobalite

Fubini, Bice, Zanetti, Giovanna, Altilia, Serena, Tiozzo, Roberta, Lison, Dominique, Saffiotti, Umberto

Journal:

Chemical Research in Toxicology

Year:

1999

Language:

english

File:

PDF, 102 KB

english, 1999

29

Clonal proliferation of rat tracheal epithelial cells in serum-free medium and their responses to hormones, growth factors and carcinogens

Thomassen, David G., Saffiotti, Umberto, Kaighn, M.Edward

Journal:

Year:

1986

Language:

english

File:

PDF, 717 KB

english, 1986

30

Antioxidant activity of tetrandrine and its inhibition of quartz‐induced lipid peroxidation

Shi, Xianglin, Mao, Yan, Saffiotti, Umberto, Wang, Liying, Rojanasakul, Yongyut, Leonard, Stephen S., Vallyathan, Val

Journal:

Journal of Toxicology and Environmental Health

Year:

1995

Language:

english

File:

PDF, 886 KB

english, 1995

31

Cellular uptake and metabolic reduction of pentavalent to trivalent arsenic as determinants of cytotoxicity and morphological transformation

Bertolero, Federico, Pozzi, Giovanni, Sabbioni, Enrico, Saffiotti, Umberto

Journal:

Year:

1987

Language:

english

File:

PDF, 552 KB

english, 1987

32

-nitrosoguanidine in the BALB/3T3 clone A31-1-1 cell line

Bignami, Margherita, Saffiotti, Umberto

Journal:

Year:

1983

Language:

english

File:

PDF, 584 KB

english, 1983

33

Dietary Cooked Navy Beans and Their Fractions Attenuate Colon Carcinogenesis in Azoxymethane-Induced Ob/Ob Mice

Bobe, Gerd, Barrett, Kathleen, Mentor-Marcel, Roycelynn, Saffiotti, Umberto, Young, Matthew, Colburn, Nancy, Albert, Paul, Bennink, Maurice, Lanza, Elaine

Journal:

Nutrition and Cancer

Year:

2008

Language:

english

File:

PDF, 118 KB

english, 2008

34

Scientific bases of environmental carcinogenesis and cancer prevention: Developing an interdisciplinary science and facing its ethical implications

Saffiotti, Umberto

Journal:

Journal of Toxicology and Environmental Health

Year:

1977

Language:

english

File:

PDF, 851 KB

english, 1977

35

Identification and definition of chemical carcinogens: Review of criteria and research needs

Saffiotti, Umberto

Journal:

Journal of Toxicology and Environmental Health

Year:

1980

Language:

english

File:

PDF, 2.33 MB

english, 1980

36

Estimation of risks of irreversible, delayed toxicity

Hoel, David G., Gaylor, David W., Kirschstein, Ruth L., Saffiotti, Umberto, Schneiderman, Marvin A.

Journal:

Journal of Toxicology and Environmental Health

Year:

1975

Language:

english

File:

PDF, 1.32 MB

english, 1975

37

The problem of extrapolating from observed carcinogenic effects to estimates of risk for exposed populations

Saffiotti, Umberto

Journal:

Journal of Toxicology and Environmental Health

Year:

1980

Language:

english

File:

PDF, 1.50 MB

english, 1980

38

Supplement 2. Second international symposium on silica, silicosis and cancer || Direct interaction between crystalline silica and DNA – a proposed model for silica carcinogenesis

Lambert N Daniel, Yan Mao, A Olufemi Williams and Umberto Saffiotti

Journal:

Scandinavian Journal of Work Environment & Health

Year:

1995

Language:

english

File:

PDF, 852 KB

english, 1995

39

Supplement 2. Second international symposium on silica, silicosis and cancer || Transforming growth factor β1, ras and p53 in silica-induced fibrogenesis and carcinogenesis

A Olufemi Williams and Umberto Saffiotti

Journal:

Scandinavian Journal of Work Environment & Health

Year:

1995

Language:

english

File:

PDF, 1.38 MB

english, 1995

40

Supplement 2. Second international symposium on silica, silicosis and cancer || Preface

David F Goldsmith, Gregory R Wagner, Umberto Saffiotti, Jean Rabovsky and James Leigh

Journal:

Scandinavian Journal of Work Environment & Health

Year:

1995

Language:

english

File:

PDF, 213 KB

english, 1995

41

Laryngeal cancer in non-smoking and non-drinking patients

León, Xavier, Rinaldo, Alessandra, Saffiotti, Umberto, Ferlito, Alfio

Journal:

Acta Oto-Laryngologica

Year:

2004

Language:

english

File:

PDF, 245 KB

english, 2004

42

Lung cancer induction by crystalline silica: Relationships to granulomatous reactions and host factors

Saffiotti, Umberto, Stinson, Sherman F.

Journal:

Environmental Carcinogenesis Reviews

Year:

1988

Language:

english

File:

PDF, 1.36 MB

english, 1988

43

Panel discussion: Extrapolation from animal experiments to humans

Bogovski, Pavel, Fishbein, Larry, Holmberg, Bo, Infante, Peter, Montesano, Ruggero, Ramel, Claes, Saffiotti, Umberto, Sorsa, Marja

Journal:

Journal of Toxicology and Environmental Health

Year:

1980

Language:

english

File:

PDF, 781 KB

english, 1980

44

Evaluation of Mixed Exposure to Carcinogens and Correlations of in vivo and in vitro Systems

Umberto Saffiotti

Journal:

Environmental Health Perspectives

Year:

1983

File:

PDF, 1.48 MB

1983

45

Evaluation of Mixed Exposure to Carcinogens and Correlations of in vivo and in vitro Systems

Umberto Saffiotti

Journal:

Environmental Health Perspectives

Year:

1983

Language:

english

File:

PDF, 1.48 MB

english, 1983

46

Supplement 2. Second international symposium on silica, silicosis and cancer || Future research needs in the silica, silicosis and cancer field

David F Goldsmith, Gregory R Wagner, Umberto Saffiotti, Jean Rabovsky and James Leigh

Journal:

Scandinavian Journal of Work Environment & Health

Year:

1995

Language:

english

File:

PDF, 525 KB

english, 1995

47

Detection and Cellular Localization of Lead by Electron Probe Analysis in the Diagnosis of Suspected Lead Poisoning in Rhesus Monkeys

Sass, Bernard, Banfield, William G., Saffiotti, Umberto

Journal:

Toxicologic Pathology

Year:

1991

File:

PDF, 792 KB

1991

48

Generation of Reactive Oxygen Species by Quartz Particles and Its Implication for Cellular Damage

Shi, Xianglin, Mao, Yan, Danie, Lambert N., Saffiotti, Umberto, Dalal, Nar S., Vallyathan, Val

Journal:

Applied Occupational and Enviromental Hygiene

Year:

1995

Language:

english

File:

PDF, 890 KB

english, 1995

49

Protective Effects of Silanol Group Binding Agents on Quartz Toxicity to Rat Lung Alveolar Cells

Mao, Yan, Daniel, Lambert N., Knapton, Alan D., Shi, Xianglin, Saffiotti, Umberto

Journal:

Applied Occupational and Enviromental Hygiene

Year:

1995

Language:

english

File:

PDF, 777 KB

english, 1995

50

Growth Factors and Gene Expression in Silica-Induced Fibrogenesis and Carcinogenesis

Williams, A. Olufemi, Knapton, Alan D., Saffiotti, Umberto

Journal:

Applied Occupational and Enviromental Hygiene

Year:

1995

Language:

english

File:

PDF, 3.52 MB

english, 1995